2025 rs660 is a single nucleotide polymorphism (SNP) positioned on chromosome 1 within the human genome. SNPs are variations in a single nucleotide that happen at a particular place within the DNA sequence. The 2025 rs660 SNP entails a change from a cytosine (C) to a thymine (T) nucleotide at place 2025 within the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR).
The MTHFR enzyme performs an important position within the metabolism of folate, a B vitamin that’s important for varied bodily features, together with DNA synthesis, cell development, and amino acid metabolism. The 2025 rs660 SNP can lead to decreased MTHFR enzyme exercise, which may result in lowered folate ranges and an elevated danger of sure well being situations, corresponding to neural tube defects in newborns and heart problems in adults.